DELIVERING INNOVATION TO CRYOPRESERVATION 
              ...without liquid nitrogen or any other cryogen

                           


     "The Home of the Grant Asymptote controlled rate freezers"

 CONTROL RATE FREEZING // STORING CRYOVIALS IN LN₂ 

Cell Cryogenics Ltd is proud to offer unique and class-leading products for cryopreservation including the Grant Asymptote EF600 - the next generation of LN₂-free controlled rate freezers.

Cell Cryogenics will be pleased to discuss your application and needs in detail and arrange an evaluation. We will ensure that you receive the best possible support and service to really appreciate the benefits of the EF600 and our other advanced cryopreservation products!

 OPTIMISING CRYOPRESERVATION, CONSULTANCY₂ 

Is your cryopreservation process optimised?   Maximum viability?   Phenotype maintained?   GMP-compliant?

CRYOPRESERVATION. The process of cryopreservation has a number of effects on a cell, some of these are well characterised. Optimising the process can have a significant effect not only on post-thaw viability but also the phenotype, phenotype stability and expansion capability.
 
CELL VIABILITY ASSESSMENT.  The viability as assessed by a standard live/dead assay does not inform as to the exact status of the cell. Further genetic, proteomic and surface marker tests will elucidate up-and down-gene regulation, changes to the secrotome and, the functional phenotype.

Cell Cryogenics Ltd can be engaged to effectively optimise your cryopreservation procedures to ensure that your cells post-cryopreservation, more closely represent the stable functional phenotype the cells were selected for.

Different versions of the EF600

EF600 100; EF600 102; EF600 108

Evaluations: your decision to buy and routinely use an EF600 should be based on the data you have generated and your experience of using a unit. We will try to ensure you are able to evaluate a unit whenever possible with support that enables you to get the most of the trial quickly.

References:  the EF600 is rapidly becoming established as the next generation of controlled rate freezers and we have many satisfied users over varied applications whose details we will be happy to provide.

Future products?: 
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# MF2000 AND MF6000 > MF2000 due for release end 2012/ early 2013 - deliver standardised and fully compliant cryopreservation for larger batches and volumes e.g.
200 - 600 cryovials per batch  or,
2 - 6 x 500 ml cryocyte bags (nom. 100 ml per bag)

The new MF controlled rate freezer models will expand the controlled rate freezer range building on the proven tract record of the EF600. They will permit standardised and optimised cryopreservation for larger cell and batch quantities including cell library formation, master cell banking, autologous and non-autologous cell therapies.

CONTACT US - for updates on the clinical trial results and availability for an evaluation.


# NucleoC > Available end 2012 - controls and optimises when ice nucleation occurs. This prevents 'supercooling' and improves both post-thaw cell viability and stability of the phenotypic functionality for a wide range of cell types. The improvement in cell viability can be significant, e.g. 30% for T-lymphocytes and enures all samples receive the optimum treatment.

CONTACT US - for updates and test samples.



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To support the need for improved cryopreservation across the scientific and medical sectors, Cell Cryogenics Ltd will continue to bring you new, innovative products - such as the forthcoming MF range above. These will not only improve the process of cryopreservation but without liquid nitrogen (LN₂) or any other cryogen such as alcohol, will fully meet the guidelines of the European Tissue and Cell Directive and the requirements of EU GMP compliance. Such products are designed from consultations with scientists, clinicians and researchers - hopefully they will be relevant to your work and of interest...PLEASE VISIT THIS SITE FOR UPDATES